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In Vitro Fertilization (IVF) and Other Infertility Treatments You May Need to Get Pregnant

If there are problems with sperm

If your partner’s sperm count is low or the sperm are slow-moving, intrauterine insemination (intrauterine insemination) or artificial insemination (in vitro fertilization) may be recommended. With IUI, a high concentration of high-quality sperm cells – collected from your partner or from a donor – are inserted directly into the uterus around the time of ovulation. Before insemination, you can take fertility drugs (such as clomiphene) to stimulate ovulation. Since the IUI procedure is time-limited to follow up on detecting ovulation, there is a better chance that the egg and sperm will find each other and pregnancy will occur. The actual insemination procedure is simple and quick and can be done in a doctor’s office or in a fertility clinic – without anaesthesia. (May cause mild cramping but not pain.) (3And the4)

In vitro fertilization (IVF) is RMost Popular Fertility Treatment

In vitro fertilization (IVF) is a much more complex procedure – one of the most popular and effective forms of antiretroviral therapy. It involves using a combination of fertility drugs (to make your eggs mature and ready for fertilization) and surgical procedures.

First steps of IVF treatments

Before ovarian stimulation occurs, the first step is often for a woman to suppress ovarian function by taking birth control pills or injecting a GnRH (gonadotropin-releasing hormone) agonist medication, such as Lupron (leuprolide), into her body for one to four weeks to prevent it from releasing Hormones that can stimulate natural ovulation. (5)

Get fertility injections and tests that monitor hormone levels and egg production

Then, the woman will begin giving herself daily injections of fertility drugs to help her ovaries produce several mature, viable eggs. During this stage, she may have regular blood tests to measure her hormone levels and ultrasounds to monitor egg production. When blood tests and ultrasound measurements indicate the eggs are “ready,” it’s time for her to get an injection of human chorionic gonadotropin (HCG) to stimulate ovulation. (2,3,4)

Egg retrieval, insemination and other IVF steps

Once the ovaries produce enough mature eggs, the doctor will remove the eggs through a minimally invasive procedure (called oocyte retrieval), either in a doctor’s office or in a fertility clinic. (You will likely be given medication to help you relax and feel comfortable during the procedure.) (4) The eggs are then mixed with the sperm of your partner (or donor) in a dish in the laboratory (a step called insemination); They are kept together in a special container so that fertilization can occur and the cells in the fertilized eggs can divide and grow into embryos.

Male Infertility Procedures (Male Factor Procedures)

With an additional procedure called ICSI (short for intracytoplasmic sperm injection), a single sperm is injected into a mature egg to help during IVF. ICSI is most commonly used when a couple is dealing with male infertility, whether it is due to low sperm count, poor motility (motility) or poor sperm quality. (6)

Embryo transfer and pregnancy test

Within about five days of egg retrieval, the doctor will place one or more embryos in the uterus in a procedure called embryo transfer; This can be done in a doctor’s office or at a fertility clinic. If any of the embryos attach to the lining of your uterus, you will get pregnant. After the embryo transfer, women sometimes take daily doses of progesterone for the first 8 to 10 weeks to support implantation and survival of the embryo in the womb. (2,4) About two weeks after the embryo transfer procedure, the woman will have a blood or urine test to detect the hormone HCG in her body; The presence of hCG indicates pregnancy.

Prepare for recurrence: Multiple IVF treatment cycles may be required

For many women, more than one cycle of IVF treatment – that is, transfer of a new embryo – is necessary before conception. (5) Approximately 27 percent of IVF cycles will result in a live birth, and while many different factors can influence the chances of success, a woman’s age is the largest. (5,8) a A study published in September 2018 in human reproduction It found that at age 30, a woman with two-year primary infertility who begins ICSI treatment for male infertility has a 40 percent chance of a live birth from the first full IVF cycle and a 72 percent chance after three complete cycles.

Gamete intra-auditory transfer (GIFT) and other possible next steps

If these fertility treatments don’t work, there may be other options. If a woman has a healthy fallopian tube, she may be a candidate for intra-fallopian gamete transfer (GIFT), which involves retrieving the woman’s eggs and transferring them with sperm to the fallopian tube so that fertilization can occur inside the woman’s body; The woman is then given a drug to build up the lining of her womb to support implantation of the fertilized egg. (9,10)

Donor eggs, donor embryos, and more IVF variants

Other potential interventions may include the use of an egg from a donor (harvested from another woman’s ovary, usually a younger one) or a donor embryo (from a couple who had IVF, got pregnant, and did not want or need unused fertilized eggs). (10) In addition, the use of a carrier or a surrogate (a woman who agrees to implant a couple’s fertilized egg into her uterus and subsequently conceive) may be an option. It is important to remember that the carrier is not biologically related to the baby because it does not provide the egg – this is a common misconception. (11)

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